NeoCHROM — modern chromatographs and custom instruments

Ukrainian manufacturer of chromatographic equipment

NeoChrom gas chromatographs

NeoChrom develops and manufactures gas chromatographs, GC-MS systems and application-specific chromatographic systems for laboratories and industry.

Instruments can be equipped with various detectors, sample introduction systems, capillary and packed columns, autosamplers and dedicated software.

What is a chromatograph?

A chromatograph is an analytical device that allows qualitative and quantitative analysis of the components of mixtures, as well as determining the content of specified substances in the sample under study.

They say: the column is the heart of the chromatograph, the detector is its brain, and the injector is its Achilles heel. It is in the column that the mixture is separated, the detector forms an analytical signal, and errors during sample introduction can spoil even a properly configured method.

The main separation of the mixture takes place in the chromatographic column: its components move at different speeds due to different interactions with the mobile and stationary phases.

After separation, the components are sequentially sent to the detector, which converts their appearance into an analytical signal. The signal is recorded and processed by specialized software.

For more reliable identification of substances, spectrometric detectors are used, primarily a mass spectrometric detector in GC-MS systems. In this case, additional structural and analytical information is obtained for each chromatographic peak — the mass spectrum of the substance. The combined use of retention time or index and spectral data significantly increases the confidence of identification compared to retention time alone.

Simply put, after chromatographic analysis, we can answer two main questions:

what was in the sample and how much of each component was in it.

What is gas chromatography?

Gas chromatography (GC — Gas Chromatography) is a physico-chemical method of separation, identification and quantification of the components of a mixture, in which the mobile phase is a carrier gas, and the stationary phase is a solid sorbent or a non-volatile liquid or polymer phase applied to the surface of the carrier or the inner wall of a capillary column.

Separation of components occurs due to their different interaction with the stationary phase and, accordingly, different residence time in the chromatographic column. Depending on the nature of the stationary phase, gas-adsorption and gas-liquid chromatography are distinguished.

The method is used for the analysis of gases, volatile and semi-volatile organic compounds, as well as substances that can be converted into volatile and thermally stable derivatives, for example by derivatization.

Gas chromatography is widely used for the analysis of natural gas, petroleum products, organic solvents, food products, drugs, biological objects, environmental pollutants, and process gas mixtures.

Which detectors are used in gas chromatography?

Flame ionization detector — FID

One of the most common detectors for determining organic compounds.

Used for analysis:

• hydrocarbons;
• solvents;
• petroleum products;
• fatty acids;
• organic impurities.

Thermal conductivity detector — TCD

Universal detector suitable for permanent gases and substances for which non-destructive detection is required.

Typical analytes:

• hydrogen;
• oxygen;
• nitrogen;
• CO;
• CO₂;
• process gas mixtures.

Electron capture detector — ECD

Highly sensitive selective detector for electronegative compounds.

Typical applications:

• organochlorine compounds;
• pesticides;
• halogenated solvents;
• environmental control.

Other selective detectors

Depending on the analytical task, the gas chromatograph can be equipped with other types of detectors.

Mass spectrometric detection — GC-MS

The combination of a gas chromatograph with a mass spectrometer allows not only to separate the components of the mixture, but also to obtain their mass spectra.

Gas chromatography–mass spectrometry GC-MS especially effective for identification of unknown substances and complex multicomponent mixtures.

GC-MS is used in:

• forensic science;
• toxicology;
• environmental analysis;
• pharmaceutical control;
• petrochemistry;
• analysis of food products;
• scientific research.

Ask about NeoChrom GC-MS systems →

How to select a chromatographic detector

The chromatograph configuration is determined not only by the detector, but also by the type of sample, required detection limit, concentration range, column, and method of sample introduction.

Where are gas chromatographs used?

• chemical industry;
• petrochemistry;
• natural gas and energy;
• pharmaceutical industry;
• food industry;
• environmental monitoring;
• toxicology;
• forensic science;
• medicine;
• scientific research;
• control of technological processes.

NeoChrom specialized solutions

Why NeoChrom?

NeoChrom is a Ukrainian developer and manufacturer of chromatographic and analytical equipment.

• in-house chromatograph development;
• modern electronic and software platform;
• warranty for new equipment up to 7 years;
• device configuration for an analytical task ;
• development of non-standard equipment;
• development and implementation of analysis methods;
• modernization of existing chromatographs ;
• commissioning and staff training;
• service support.

Metrology and quality management

NeoChrom's quality management system covers the design, manufacture, setup and control of chromatographic equipment according to established procedures.

The set of documents is determined by the model, configuration of the device, its metrological purpose and scope of application.

Frequently asked questions

Select a chromatograph

Describe the sample type, analytes, expected concentrations and applicable standard method. NeoChrom engineers will recommend an instrument configuration for your analytical application.